منابع مشابه
Purines and Carotid Body: New Roles in Pathological Conditions
It is known that adenosine and adenosine-5'-triphosphate (ATP) are excitatory mediators involved in carotid body (CB) hypoxic signaling. The CBs are peripheral chemoreceptors classically defined by O2, CO2, and pH sensors. When hypoxia activates the CB, it induces the release of neurotransmitters from chemoreceptor cells leading to an increase in the action potentials frequency at the carotid s...
متن کاملThe Carotid Sinus and Respiration
INTRODUCTION. SOME time ago in this Journal, Boydl described the results of recent work on the carotid sinus mechanism chiefly in regard to its effect on the circulation. 'The carotid sinus is also known to exert an important inifluence on respiration, and in this article it is desired to give an account of sonme of the work dealing with this aspect of its function, and to draw attention to the...
متن کاملHypoxia and the carotid body.
Since the publication of the classical studies of Heymans et al (1930) it has been accepted that the carotid body is a chemoreceptor which monitors the oxygen tension of systemic arterial blood, and it has been extensively investigated by physiologists (Biscoe, 1971). Because chronic hypoxia is a major hazard of life at high altitude and of cardiorespiratory disease at sea level, it might be th...
متن کاملThe aging carotid body.
The respiratory system is subject to the aging process, which could limit its responsiveness to hyperventilatory stimuli. Attenuation of the ventilatory response to hypoxia in old age is, as yet, an unresolved issue. Such attenuation may be germane for the pathogenesis of respiratory disorders developing more often in elderly subjects. The aim of this study was to determine the potential advers...
متن کاملStimulation of the Respiration of Chlorella Vulgaris by Purines and Purine Analogues.
[In the course of studies of the inicorporation of adenine-8-C14 into the nucleic acids of Chlorella vtilgaris we observed an unexpectedly large formation of C'402 by the cultures in the dark. \When the oxidation of adenine in this system wvas followed manometrically, it was found that Up to 10 or 20 times more oxygen was taken up by the cells than could be accounted for by assuming the conmple...
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ژورنال
عنوان ژورنال: Respiratory Physiology & Neurobiology
سال: 2007
ISSN: 1569-9048
DOI: 10.1016/j.resp.2007.02.015